Sermolina

Sermorelin Acetate – Premium Research Peptide

Sermorelin Acetate is a synthetic peptide consisting of the first 29 amino acids of the endogenous GHRH sequence (1-29). This truncated GHRH analog retains full biological activity at the GHRH receptor while offering improved stability compared to the native 44-amino acid sequence. Sermorelin has been extensively studied as a tool for investigating GHRH receptor signaling and endocrine pathway physiology.

This product is intended for laboratory and research purposes only. Research Use Only.

Molecular Characteristics

Sermorelin contains the minimum sequence required for full GHRH receptor activation. The peptide sequence (Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH₂) binds to GHRH receptors, engaging downstream signaling cascades.

Research Applications

Sermorelin has been studied extensively in preclinical research for its effects on GHRH receptor-mediated signaling. The peptide provides researchers with a tool for investigating:

• GHRH receptor binding, activation, and signaling
• Receptor-mediated endocrine signaling cascades
• Pulsatile signaling dynamics and release patterns
• Downstream pathway modulation in research models
• Endocrine axis physiology and feedback mechanisms
• Temporal changes in GHRH receptor responsiveness
• Structure-activity relationships in GHRH analogs

Research indicates Sermorelin activates GHRH receptors in a pulsatile manner, maintaining normal feedback mechanisms and making it valuable for studying receptor-mediated signaling dynamics.

Technical Specifications

• Sequence: GHRH (1-29) NH₂
• CAS Number: 86168-78-7
• Molecular Formula: C₁₄₉H₂₄₆N₄₄O₄₂S
• Molecular Weight: 3,357.9 g/mol
• Amino Acids: 29
• Purity: ?99%
• Form: Lyophilized powder (acetate salt)
• Storage: Store at -20°C, protected from light