Description:
5-Amino-1MQ (5-amino-1-methylquinolinium) is a synthetic small-molecule NNMT inhibitor investigated in controlled laboratory research for its role in NAD⁺ metabolism, methylation balance, and cellular energy regulation. NNMT (nicotinamide N-methyltransferase) is an enzyme expressed across metabolically active tissues including adipose, liver, and skeletal muscle. By limiting NNMT’s consumption of nicotinamide, 5-Amino-1MQ preserves substrate availability for NAD⁺ biosynthesis, making it a compound of interest in research examining metabolic pathway modulation, fat cell signaling, and longevity-associated enzyme activity.
Scientific Specifications:
- Compound Name: 5-Amino-1MQ (5-amino-1-methylquinolinium)
- Type: Small Molecule (Non-peptide)
- Molecular Formula: C₁₀H₁₁N₂
- Molecular Weight: 159.21 g/mol
- CAS Number: 42464-96-0
- PubChem CID:950107
- Form: Lyophilized powder
- Storage: Store dry in a cool, dark environment (2°C to 8°C)
Research Context:
5-Amino-1MQ is commonly studied for its potential effects on:
- NNMT inhibition and methylation cycle modulation
- NAD⁺ metabolism and intracellular energy homeostasis
- Adipocyte differentiation and lipolysis regulation
- Insulin sensitivity and glucose metabolism
- Sirtuin (SIRT1) pathway activation and longevity-associated signaling
- Skeletal muscle satellite cell biology and regenerative markers
Intended Use:
This product is intended strictly for laboratory research applications only by qualified scientific personnel. It is not approved for human or animal consumption, and may not be used in foods, drugs, supplements, cosmetics, or diagnostics.
Legal Disclaimer:
The statements provided and this compound have not been evaluated by the U.S. Food and Drug Administration. No claims are made regarding diagnosis, treatment, or prevention of any disease. Use is restricted to qualified researchers operating in certified laboratory environments.
Terms of Sale:
By purchasing this product, the buyer affirms they are a qualified researcher or institutional purchaser, fully responsible for proper handling, storage, and legal compliance.
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