CJC-1295 (NO DAC)

For Research Use Only | Not for Human or Veterinary Use

Description:
CJC-1295 without DAC (Drug Affinity Complex), also known as Modified GRF (1-29) or Mod GRF 1-29, is a synthetic 29-amino-acid analogue of growth hormone-releasing hormone (GHRH). It features four amino acid substitutions (D-Ala², Gln⁸, Ala¹⁵, Leu²⁷) engineered to resist enzymatic degradation while maintaining strong GHRH receptor activity. Unlike the DAC-conjugated variant, this form promotes pulsatile growth hormone release patterns that more closely mimic endogenous physiological secretion, making it a widely used tool in GH-axis research.

Scientific Specifications:

• Peptide Name: CJC-1295 without DAC (Modified GRF 1-29)
• Type: Synthetic GHRH Analogue (29 amino acids)
• Sequence: Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH₂
• Molecular Formula: C₁₅₂H₂₅₂N₄₄O₄₂
• Molecular Weight: ~3367.9 g/mol
• CAS Number: 863288-34-0
• PubChem CID:133630236
• Form: Lyophilized powder
• Storage: Store dry in a cool, dark environment (2°C to 8°C)

Research Context:
CJC-1295 (No DAC) is commonly studied for its potential effects on:

• Pulsatile growth hormone (GH) release mimicking physiological secretion patterns
• IGF-1 elevation and downstream anabolic signaling pathways
• Body composition modulation, including lean mass and fat metabolism
• GHRH receptor activation and adenylate cyclase/cAMP signaling
• Post-exercise recovery and tissue regeneration models
• Synergistic effects when combined with GH secretagogues (e.g., Ipamorelin, GHRP-6)

Intended Use:
This product is intended strictly for laboratory research applications only by qualified scientific personnel. It is not approved for human or animal consumption, and may not be used in foods, drugs, supplements, cosmetics, or diagnostics.

Legal Disclaimer:
The statements provided and this compound have not been evaluated by the U.S. Food and Drug Administration. No claims are made regarding diagnosis, treatment, or prevention of any disease. Use is restricted to qualified researchers operating in certified laboratory environments.