NAD+

NAD+ (Nicotinamide Adenine Dinucleotide) – Premium Research Compound

NAD+ (Nicotinamide Adenine Dinucleotide) is a critical coenzyme found in all living cells, serving as an essential cofactor in numerous metabolic reactions. This dinucleotide has become a focal point in metabolism, redox biology, and cellular energy research due to its central role in redox reactions and its function as a substrate for NAD-consuming enzymes.

This product is intended for laboratory and research purposes only. Research Use Only.

Molecular Characteristics

NAD+ consists of two nucleotides joined through their phosphate groups—one containing an adenine base and the other containing nicotinamide. The molecule exists in oxidized (NAD+) and reduced (NADH) forms, cycling between these states during metabolic processes. Endogenous NAD+ concentrations have been shown to vary across biological samples, making it a significant focus of metabolic and enzymatic research.

Research Applications

NAD+ has been extensively studied in various research contexts including:

• Cellular energy metabolism and mitochondrial function
• Sirtuin enzyme activation and regulation (SIRT1-7)
• DNA repair mechanisms through PARP enzyme activity
• Circadian rhythm regulation and metabolic homeostasis
• NAD+ flux dynamics across experimental models
• Neuronal signaling and NAD+-dependent pathway studies
• Metabolic pathway analysis and enzymatic studies

Research indicates NAD+ serves as a substrate for several important enzyme families including sirtuins, PARPs, and CD38, linking it to diverse cellular processes from gene expression to enzymatic regulation.

Technical Specifications

• CAS Number: 53-84-9
• Molecular Formula: C₂₁H₂₇N₇O₁₄P₂
• Molecular Weight: 663.43 g/mol
• Purity: ?99%
• Form: Lyophilized powder
• Appearance: White to off-white powder
• Storage: Store at -20°C, protected from light and moisture