KPV

For Research Use Only | Not for Human or Veterinary Use

Description:
KPV (Lys-Pro-Val) is a naturally derived tripeptide originating from the C-terminal of alpha-melanocyte stimulating hormone (α-MSH). It is extensively studied for its potent anti-inflammatory properties in preclinical models, particularly within the gastrointestinal tract and skin. KPV exerts its effects through melanocortin receptor (MC1R/MC3R) activation and NF-κB pathway inhibition, reducing pro-inflammatory cytokine expression without the melanogenic side effects associated with full-length α-MSH.

Scientific Specifications:

• Peptide Name: KPV (Lys-Pro-Val, α-MSH C-Terminal Fragment)
• Type: Naturally Derived Tripeptide (3 amino acids)
• Sequence: Lys-Pro-Val
• Molecular Formula: C₁₆H₃₀N₄O₄
• Molecular Weight: ~342.43 g/mol
• CAS Number: 67727-97-3
• Form: Lyophilized powder
• Storage: Store dry in a cool, dark environment (2°C to 8°C)

Research Context:
KPV is commonly studied for its potential effects on:

• Anti-inflammatory signaling via melanocortin receptor (MC1R/MC3R) activation
• NF-κB pathway inhibition and pro-inflammatory cytokine reduction
• Gastrointestinal inflammation and colitis research models
• Skin inflammation and contact dermatitis models
• TNF-α and IL-6 suppression in systemic inflammation
• Immune modulation without melanogenic side effects of full-length α-MSH

Intended Use:
This product is intended strictly for laboratory research applications only by qualified scientific personnel. It is not approved for human or animal consumption, and may not be used in foods, drugs, supplements, cosmetics, or diagnostics.

Legal Disclaimer:
The statements provided and this compound have not been evaluated by the U.S. Food and Drug Administration. No claims are made regarding diagnosis, treatment, or prevention of any disease. Use is restricted to qualified researchers operating in certified laboratory environments.

Terms of Sale:
By purchasing this product, the buyer affirms they are a qualified researcher or institutional purchaser, fully responsible for proper handling, storage, and legal compliance.